Progress in Omics

analysis blind spot dataset
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2D chemical structures of six poly(ADP-ribose) polymerase (PARP) inhibitors used in this study. Top row include three FDA approved compounds (olaparib, rucaparib, and talazoparib), bottom row include

Tour de Force Proteomics Dataset Reveals New Clues to Small Molecule Mechanism of Action (MOA) and Off-Target Effects

October 17th, 2023

A new study used proteomics to decipher the mechanisms of action of 875 drugs, providing a valuable resource for understanding how drugs work and developing more targeted and effective therapies.

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blind spot dataset
Colorized scanning electron micrograph of Group A Streptococcus (Streptococcus pyogenes) bacteria (yellow) and a human neutrophil (blue). Credit: NIAID

Cancer Microbiome Reanalysis

August 28th, 2023

A bioXriv preprint contends that a 2020 paper linking bacteria to cancer was based on flawed data analyses.

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analysis blind spot

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